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Curry
cure? Spicing up the effectiveness of a
potential Disease Fighter
Newswise — Scientists are reporting development of a nano-size
capsule that boosts the body’s uptake of
curcumin, an ingredient in yellow curry now
being evaluated in clinical trials for
treatment of several diseases.
Their study is in ACS’ Journal of Agricultural and Food
Chemistry, a bi-weekly publication.
Koji Wada and colleagues note that curcumin is a potent
antioxidant found in the spice, turmeric.
Clinical trials are checking its safety and
effectiveness for colon cancer, psoriasis,
and Alzheimer’s disease.
However, digestive juice in the gastrointestinal tract
quickly destroys curcumin so that little
actually gets into the blood.
Scientists have known for years that encapsulating insulin
and certain other drugs into structures
called liposomes can boost absorption. The
scientists prepared the liposomes
encapsulating curcumin and fed them to
laboratory rats.
Encapsulating more than quadrupled absorption of curcumin,
and also boosted antioxidant levels in the
blood. The encapsulating process could be an
answer to the problem of increasing
curcumin’s absorption in the digestive
environment of the gastrointestinal tract,
they suggest.
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