The study was conducted by David W. DeGroot and
W. Larry Kenney of the Intercollege Graduate
Degree Program in Physiology and Noll
Laboratory, Pennsylvania State University,
University Park, PA; and George Havenith,
Department of Human Sciences, Loughborough
University, Loughborough, UK. Their study,
entitled “Responses to Mild Cold Stress Are
Predicted by Different Individual
Characteristics in Young and Older
Subjects,” appears in the December edition
of the Journal of Applied Physiology
(http://jap.physiology.org/).
Summary of the Study
Ten Characteristics and Body Core
Temperature
The study examined the relative influence of
ten physical characteristics thought
potentially to play a role in how the body’s
core temperature and tissue insulation react
to cold. The characteristics they reviewed
were age, sex, weight, body surface area,
body surface area-to-mass ratio, sum of skin
folds (an estimate of body fat), percent
body fat, appendicular skeletal muscle mass
(ASMM), and two thyroid hormone
concentrations, T3 and T4.
Forty-two young (18-30 years; 21 men, 21 women)
and 46 older (65-89 years; 24 men, 22 women)
individuals participated. The volunteers
were nonsmokers and took no medications that
could alter their cardiovascular or
thermoregulatory responses to cool
temperatures. Participants underwent a
standardized medical screening and physical
exam, and researchers measured or calculated
the ten physical characteristics noted above
for each subject.
Researchers then inserted a thermometer sealed
in a pediatric feeding tube into each
participant who then entered a controlled
environmental chamber and was positioned in
a reclining position. The room’s baseline
temperature remained stable for 20 minutes
and was decreased thereafter at a rate of
0.2°C per minute for 20 minutes and 0.05°C
per minute after that to approximate mild
cold exposure. The participants were removed
when visible, sustained shivering was
observed by the investigators or reported by
the volunteer.
Multiple-regression analyses were performed to
determine the predictors of body temperature
and tissue insulation, and standardized
regression coefficients were analyzed to
determine the relative influence of each of
the ten candidate variables.
Findings and Conclusions
The researchers observed the following:
in young subjects, percent body fat and T3
hormone explained most of the variance in
body temperature response to cold. Among
older persons, the percent of body fat, the
skeletal muscle mass, or both was
responsible for similar amounts of
variability in the response to cold;
the sum of skin folds was responsible for 67
percent (P<0.01) of the body temperature
variance in young subjects versus two
percent of the body temperature variation in
older subjects;
unexplained variance of body temperature to
cold was considerably less in younger
participants (14-42 percent) than in older
participants (59-72 percent).
These results suggest that the well known
changes in body composition characteristics
with aging in turn influence how the body
deals with the cold as we grow older.
Characteristics that are important in young
people become less important with aging, and
previously-insignificant characteristics
rise in importance.