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wine compound shown to prevent prostate
Newswise — Researchers
at the University of Alabama at Birmingham (UAB)
have found that nutrients in red wine may
help reduce the risk of developing prostate
The study involved male
mice that were fed a plant compound found in
red wine called resveratrol, which has shown
anti-oxidant and anti-cancer properties.
Other sources of resveratrol in the diet
include grapes, raspberries, peanuts and
In the study
resveratrol-fed mice showed an 87 percent
reduction in their risk of developing
prostate tumors that contained the worst
kind of cancer-staging diagnosis.
The mice that proved to
have the highest cancer-protection effect
earned it after seven months of consuming
resveratrol in a powdered formula mixed with
Other mice in the
study, those fed resveratrol but still
developed a less-serious form of prostate
cancer, were 48 percent more likely to have
their tumor growth halted or slowed when
compared to mice who did not consume the
compound, the UAB research team said.
The findings were
published in August through the online
edition of the journal Carcinogenesis.
This study adds to a growing body of
evidence that resveratrol consumption
through red wine has powerful
chemoprevention properties, in addition to
its apparent heart-health benefits, said
lead study author Coral Lamartiniere, Ph.D.,
of UAB’s Department of Pharmacology and
An earlier UAB study
published May 2006 in the same journal found
resveratrol-fed female mice had considerable
reduction in their risk of breast cancer.
Lamartiniere said his research team has been
pleasantly surprised at the chemoprevention
power of wine and berry polyphenols like
resveratrol in animal models.
"A cancer prevention
researcher lives for these days when they
can make that kind of finding," Lamartiniere
said. "I drink a glass a day every evening
because I’m concerned about prostate cancer.
It runs in my family."
Lamartiniere and other
researchers say work is already underway to
test resveratrol consumption in humans to
see what concentrations are needed to convey
The amounts used in the
UAB mice studies were the equivalent of one
person consuming one bottle of red wine per
day, which is not advisable. Since drinking
alcohol in excessive amounts can have
harmful health effects, doctors generally
recommend moderate red wine consumption,
which is an average of two drinks a day for
men and one drink a day for women.
included researchers from the UAB Department
of Pathology and the Comprehensive Cancer
Center. Funding support came from the U.S.
Department of Defense and the National